ACI :: MACI :: OATS :: OC Allograft :: Microfracture :: DeNovo
Clinical Trial :: Treatment of Osteochondritis Dissecans
DeNovo® grafts are tissue grafts used in cartilage repair. These grafts consists cartilage tissue collected from donors or grown in the laboratory using human donated cartilage cells. DeNovo® grafts are of two forms — DeNovo® ET (Engineered tissue) and DeNovo® NT (natural tissue) grafts.
DeNovo® NT graft contains particulated natural articular cartilage living cells harvested from juvenile donors (aged below 13 years). Transplantation of DeNovo® NT is a simple single-step procedure where the graft is fixed on the defect area using fibrin glue and no periosteal flap is required.
DeNovo® ET is an engineered tissue graft cultured in laboratory using the cells collected from juvenile donors. The cells collected are cultured in the laboratory using cell-based technology. Juvenile cartilage cells have greater potential of regeneration than the adult cartilage cells. The graft can be placed over the defect area using single-step simple surgical procedure.